Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targetable genetic features of primary testicular and primary central nervous system lymphomas

23 Dec 2015

Abstract excerpt

Primary central nervous system lymphomas (PCNSLs) and primary testicular lymphomas (PTLs) are extranodal large B-cell lymphomas (LBCLs) with inferior responses to current empiric treatment regimens. To identify targetable genetic features of PCNSL and PTL, we characterized their recurrent somatic mutations, chromosomal rearrangements, copy number alterations (CNAs), and associated driver genes, and compared these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to CNS Lymphoma Diagnosis and Treatment
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26702065
DOI: 10.1182/blood-2015-10-673236

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targetable genetic features of primary testicular and primary central nervous system lymphomasPMID 26702065Read ↗

Testicular large B‐cell lymphoma is genetically similar to PCNSL and distinct from nodal DLBCLSemantic proximity Read ↗

Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas.Semantic proximity Read ↗

The genomic and transcriptional landscape of primary central nervous system lymphomaSemantic proximity Read ↗

The pathobiology of primary testicular diffuse large B-cell lymphoma: Implications for novel therapies.Semantic proximity Read ↗

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade.Semantic proximity Read ↗

Pathology and new insights in central nervous system lymphomas.Semantic proximity Read ↗

Frequent Gene Mutations and Their Possible Roles in the Pathogenesis, Treatment and Prognosis of Primary Central Nervous System Lymphoma.Semantic proximity Read ↗

Molecular profiling of primary renal diffuse large B-cell lymphoma unravels a proclivity for immune-privileged organ-tropismSemantic proximity Read ↗

Primary Central Nervous System Lymphoma Tumor Biopsies Show Heterogeneity in Gene Expression Profiles and Genetic SubtypesSemantic proximity Read ↗

Primary CNS lymphoma commonly expresses immune response biomarkersSemantic proximity Read ↗

Clinicopathologic and Genetic Features of Primary T-cell Lymphomas of the Central Nervous System: An Analysis of 11 Cases Using Targeted Gene Sequencing.Semantic proximity Read ↗

Genomic landscape and molecular subtypes of primary central nervous system lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.