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Article

Resequencing and association analysis of PTPRA, a possible susceptibility gene for schizophrenia and autism spectrum disorders.

PloS one - 1 Jan 2014

Xing Jingrui, Wang Chenyao, Kimura Hiroki, Takasaki Yuto, Kunimoto Shohko, Yoshimi Akira, Nakamura Yukako, Koide Takayoshi, Banno Masahiro, Kushima Itaru, Uno Yota, Okada Takashi, Aleksic Branko, Ikeda Masashi, Iwata Nakao, Ozaki Norio

Abstract excerpt

BACKGROUND: The PTPRA gene, which encodes the protein RPTP-α, is critical to neurodevelopment. Previous linkage studies, genome-wide association studies, controlled expression analyses and animal models support an association with both schizophrenia and autism spectrum disorders, both of which share a substantial portion of genetic risks. METHODS: We sequenced the protein-encoding areas of the PTPRA gene for...

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Identifiers

PMID: 25393624
DOI: 10.1371/journal.pone.0112531
PMCID: PMC4231042

Genes

PTPRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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