Article
Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia.
Journal of psychiatric research - 1 Oct 2009
van Schijndel Jessica E, van Loo Karen M J, van Zweeden Martine, Djurovic Srdjan, Andreassen Ole A, Hansen Thomas, Werge Thomas, Kallunki Pekka, Pedersen Jan T, Martens Gerard J M
Abstract excerpt
Schizophrenia is a complex neurodevelopmental disorder that is thought to be induced by an interaction between predisposing genes and environmental stressors. To identify predisposing genetic factors, we performed a targeted (mostly neurodevelopmental) gene approach involving the screening of 396 selected non-synonymous single-nucleotide polymorphisms (SNPs) in three independent Caucasian schizophrenia...
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