Article
Genetic analysis of the TrkB gene and schizophrenia in the Japanese population: Juntendo University Schizophrenia Projects (JUSP).
Neuroscience letters - 20 Sept 2007
Higashi Maiko, Higashi Shinji, Ohnuma Tohru, Shibata Nobuto, Sakai Yoshie, Arai Heii
Abstract excerpt
The presence of cognitive and social impairments during childhood and adolescence in patients with schizophrenia has lead to the widespread hypothesis that schizophrenia may be a neurodevelopmental disorder, which suggests that risk genes for schizophrenia may act through the disruption of normal neurodevelopmental processes. Moreover, recent studies indicate that TrkB, which is receptor of neurotrophins...
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