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Article

Targeted delivery of vaccine to dendritic cells by chitosan nanoparticles conjugated with a targeting peptide ligand selected by phage display technique.

Macromolecular bioscience - 1 Mar 2015

Jung Su-Na, Kang Sang-Kee, Yeo Guen-Hye, Li Hai-Ying, Jiang Tao, Nah Jae-Woon, Bok Jin-Duck, Cho Chong-Su, Choi Yun-Jaie

Abstract excerpt

The paper presents a novel dendritic cells (DC)-targeting peptide, TPAFRYS (TP) identified by phage display technique and conjugated to chitosan in order to develop an efficient DC-targeting vaccine delivery carrier. TP-conjugated chitosan nanoparticles (TPC-NPs) were prepared with ovalbumin (OVA) as a model vaccine by ionic gelation. Flow cytometry and immunocytochemistry studies demonstrated the higher...

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Identifiers

PMID: 25393207
DOI: 10.1002/mabi.201400352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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