Article
Glycodendrimers as new tools in the search for effective anti-HIV DC-based immunotherapies.
Nanomedicine : nanotechnology, biology, and medicine - 1 Oct 2013
Córdoba E Vacas, Pion M, Rasines B, Filippini D, Komber H, Ionov M, Bryszewska M, Appelhans D, Muñoz-Fernández M A
Abstract excerpt
Dendritic cells (DC), which play a major role in development of cell-mediated immunity, represent opportunities to develop novel anti-HIV vaccines. Dendrimers have been proposed as new carriers to ameliorate DC antigen loading and in this way, we have determined the potential use of maltose decorated neutrally and positively charged G4 glycodendrimers. Thus, immunostimulatory properties of these glycodendrimers...
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