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The Utility of Fluorescence In Situ Hybridization (FISH) in the Diagnosis of Myxoid Soft Tissue Neoplasms

1 Jan 2008

Abstract excerpt

Diagnosing myxoid soft tissue neoplasms can be challenging because of overlapping histologic features. Distinct chromosomal translocations have been identified in several myxoid sarcomas, including t(12;16)(q13;p11) FUS-DDIT3 in myxoid liposarcoma, t(7;16)(q34;p11) FUS-CREB3L2 in low-grade fibromyxoid sarcoma, and t(9;22)(q31;q12) EWSR1-NR4A3 in extraskeletal myxoid chondrosarcoma. These recurrent chromosomal...

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PMID: 18162764
DOI: 10.1097/pas.0b013e3181578d5a

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