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Article

Relevance of translocation type in myxoid liposarcoma and identification of a novel EWSR1‐DDIT3 fusion

23 Jul 2007

Abstract excerpt

The clinical course of myxoid/round cell liposarcoma (MRCL) is characterized by frequent local recurrences and metastases at unusual sites. MRCLs carry specific translocations, t(12;16) or rarely t(12;22), linking the FUS or the EWSR1 gene with the DDIT3 gene, respectively. Nine FUS/DDIT3 and three EWSR1/DDIT3 variants of fusion transcripts have been described thus far. In search of prognostic markers for MRCL,...

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PMID: 17647282
DOI: 10.1002/gcc.20478

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