Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DDIT3 Gene Break-apart as a Molecular Marker for Diagnosis of Myxoid Liposarcoma—Assay Validation and Clinical Experience

16 Nov 2011

Abstract excerpt

Myxoid liposarcoma with or without a round cell component is the most common subtype of liposarcoma. The diagnosis of myxoid liposarcoma could be challenging with histology, as a variety of soft tissue tumors with myxoid change might mimic myxoid liposarcoma, especially on small biopsy tissues. Chromosomal translocations of t(12,16) (q13;p11) and t(12;22) (q13;q12), rendering gene fusions of DDIT3 (previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22089349
DOI: 10.1097/pdm.0b013e3182107eb9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DDIT3 Gene Break-apart as a Molecular Marker for Diagnosis of Myxoid Liposarcoma—Assay Validation and Clinical ExperiencePMID 22089349Read ↗

Relevance of translocation type in myxoid liposarcoma and identification of a novel EWSR1‐DDIT3 fusionSemantic proximity Read ↗

The Utility of Fluorescence In Situ Hybridization (FISH) in the Diagnosis of Myxoid Soft Tissue NeoplasmsSemantic proximity Read ↗

FUS::DDIT3 Fusion Protein in the Development of Myxoid Liposarcoma and Possible Implications for TherapySemantic proximity Read ↗

Contributions of Cytogenetics and Molecular Cytogenetics to the Diagnosis of Adipocytic TumorsSemantic proximity Read ↗

Pathology and genetics of adipocytic tumorsSemantic proximity Read ↗

FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting RecommendationsSemantic proximity Read ↗

Ancillary Tools for the Diagnosis of CIC ‐Rearranged Sarcoma: A Comprehensive ReviewSemantic proximity Read ↗

Myxoid liposarcoma with nuclear pleomorphism: a clinicopathological and molecular study.Semantic proximity Read ↗

The Myxoid/Round Cell Liposarcoma Fusion Oncogene FUS-DDIT3 and the Normal DDIT3 Induce a Liposarcoma Phenotype in Transfected Human Fibrosarcoma CellsSemantic proximity Read ↗

Dual-color, Break-apart FISH Assay on Paraffin-embedded Tissues as an Adjunct to Diagnosis of Xp11 Translocation Renal Cell Carcinoma and Alveolar Soft Part SarcomaSemantic proximity Read ↗

Liposarcomas: diagnostic pitfalls and new insightsSemantic proximity Read ↗

<i>C11orf95‐MKL2</i> is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.