Genomic signature of multidrug-resistant Salmonella enterica serovar typhi isolates related to a massive outbreak in Zambia between 2010 and 2012.

doi:10.1128/JCM.02026-14

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Article

Genomic signature of multidrug-resistant Salmonella enterica serovar typhi isolates related to a massive outbreak in Zambia between 2010 and 2012.

Journal of clinical microbiology - 1 Jan 2015

Hendriksen Rene S, Leekitcharoenphon Pimlapas, Lukjancenko Oksana, Lukwesa-Musyani Chileshe, Tambatamba Bushimbwa, Mwaba John, Kalonda Annie, Nakazwe Ruth, Kwenda Geoffrey, Jensen Jacob Dyring, Svendsen Christina A, Dittmann Karen K, Kaas Rolf S, Cavaco Lina M, Aarestrup Frank M, Hasman Henrik, Mwansa James C L

Abstract excerpt

Retrospectively, we investigated the epidemiology of a massive Salmonella enterica serovar Typhi outbreak in Zambia during 2010 to 2012. Ninety-four isolates were susceptibility tested by MIC determinations. Whole-genome sequence typing (WGST) of 33 isolates and bioinformatic analysis identified the multilocus sequence type (MLST), haplotype, plasmid replicon, antimicrobial resistance genes, and genetic...

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Identifiers

PMID: 25392358
DOI: 10.1128/JCM.02026-14
PMCID: PMC4290967

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