Article
Genomic profiling of antimicrobial resistance genes in clinical isolates of Salmonella Typhi from patients infected with Typhoid fever in India.
Scientific reports - 19 May 2020
Katiyar Amit, Sharma Priyanka, Dahiya Sushila, Singh Harpreet, Kapil Arti, Kaur Punit
Abstract excerpt
The development of multidrug resistance in Salmonella enterica serovar Typhi currently forms a major roadblock for the treatment of enteric fever. This poses a major health problem in endemic regions and extends to travellers returning from developing countries. The appearance of fluoroquinolone non-susceptible strains has resulted in use of ceftriaxone as drug of choice with azithromycin being recommended for...
Topics
- Anti-Bacterial Agents
- Bacterial Proteins
- Cefixime
- Ceftriaxone
- DNA Gyrase
- DNA Topoisomerase IV
- Drug Resistance, Multiple, Bacterial
- Fluoroquinolones
- Gene Expression Regulation, Bacterial
- Humans
- India
- Microbial Sensitivity Tests
- Phenotype