High prevalence of multi-drug resistant H58 Salmonella Typhi and emerging fluoroquinolone resistance among febrile children in Nairobi County, Kenya.

doi:10.1186/s12879-025-12317-z

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Article

High prevalence of multi-drug resistant H58 Salmonella Typhi and emerging fluoroquinolone resistance among febrile children in Nairobi County, Kenya.

BMC infectious diseases - 10 Dec 2025

Kavai Susan Mutile, Mbae Cecilia, Mugo Michael, Njoroge Peter, Chepchirchir Jessica, Wambui Naomi, Anyona Steve, Imoli Diana, Ng'etich Ronald, Kibet Evans, Odityo Georgina, Mundalo Sheillah, Wairimu Celestine, Kariuki Mary, Njuguna Amos, Wamucii Evelyn, Mbithi Winfred, Owegi Darius, Muturi Peter, Kebenei Collins, Miriti Humphrey, Komen Naomi, Kioko Christine, Kawira Maureen, Kavai June, Osman Rahma, Wakio Zillah, Ongadi Beatrice, Onsare Robert, Kering Kelvin, Kariuki Samuel

Abstract excerpt

BACKGROUND: Typhoid fever is a serious infection that primarily affects humans, with approximately 20 million cases reported each year, mostly in low- and middle-income countries (LMICs). Continuous monitoring of Salmonella enterica serovar Typhi (S. Typhi) in these endemic areas is crucial for tracking trends in antimicrobial resistance (AMR) and developing effective control measures. This study focused on S....

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PMID: 41372809
DOI: 10.1186/s12879-025-12317-z
PMCID: PMC12801635

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