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Article

Genetic polymorphisms in MMP 2, 9 and 3 genes modify lung cancer risk and survival.

BMC cancer - 28 Mar 2012

González-Arriaga Patricia, Pascual Teresa, García-Alvarez Arturo, Fernández-Somoano Ana, López-Cima M Felicitas, Tardón Adonina

Abstract excerpt

BACKGROUND: Matrix metalloproteases (MMPs) are proteolytic enzymes that contribute to all stages of tumour progression, including the later stages of invasion and metastasis. Genetic variants in the MMP genes may influence the biological function of these enzymes and change their role in carcinogenesis and progression. We have investigated the association between the -735 C/T, the -1171 5A/6A, and the -1562 C/T...

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Source

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Identifiers

PMID: 22455335
DOI: 10.1186/1471-2407-12-121
PMCID: PMC3350430

Genes

MMP2
MMP9
MMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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