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Article

Circadian clock genes and risk of fatal prostate cancer.

Cancer causes & control : CCC - 1 Jan 2015

Markt Sarah C, Valdimarsdottir Unnur A, Shui Irene M, Sigurdardottir Lara G, Rider Jennifer R, Tamimi Rulla M, Batista Julie L, Haneuse Sebastien, Flynn-Evans Erin, Lockley Steven W, Czeisler Charles A, Stampfer Meir J, Launer Lenore, Harris Tamara, Smith Albert Vernon, Gudnason Vilmundur, Lindstrom Sara, Kraft Peter, Mucci Lorelei A

Abstract excerpt

PURPOSE: Circadian genes may be involved in regulating cancer-related pathways, including cell proliferation, DNA damage response, and apoptosis. We aimed to assess the role of genetic variation in core circadian rhythm genes with the risk of fatal prostate cancer and first morning void urinary 6-sulfatoxymelatonin levels. METHODS: We used unconditional logistic regression to evaluate the association of 96...

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Identifiers

PMID: 25388799
DOI: 10.1007/s10552-014-0478-z
PMCID: PMC4282953

Genes

CRY1
NPAS2
PER3
TIMELESS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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