Article
Circadian genes and risk of prostate cancer in the prostate cancer prevention trial.
Molecular carcinogenesis - 1 Mar 2018
Chu Lisa W, Till Cathee, Yang Baiyu, Tangen Catherine M, Goodman Phyllis J, Yu Kai, Zhu Yong, Han Summer, Hoque Ashraful M, Ambrosone Christine, Thompson Ian, Leach Robin, Hsing Ann W
Abstract excerpt
Circadian genes have been considered as a possible biological mechanism for the observed relationship between circadian rhythm disruptions and increased risk of hormone-related cancers. In the current study, we investigated the relationship between circadian gene variants and prostate cancer risk and whether reducing bioavailable testosterone modifies the circadian genes-prostate cancer relationship. We conducted...
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