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Article

Genetic variants in the circadian rhythm pathway as indicators of prostate cancer progression

5 Apr 2019

Abstract excerpt

To determine the association between circadian pathway genetic variants and the risk of prostate cancer progression. We systematically evaluated 79 germline variants in nine circadian pathway genes in a cohort of 458 patients with localized prostate cancer as the discovery phase. We then replicated the significant findings in another cohort of 324 men with more advanced disease. The association of each variant...

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PMID: 30996687
DOI: 10.1186/s12935-019-0811-4

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