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Article

p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis.

Experimental dermatology - 1 Feb 2015

Mollo Maria Rosaria, Antonini Dario, Mitchell Karen, Fortugno Paola, Costanzo Antonio, Dixon Jill, Brancati Francesco, Missero Caterina

Abstract excerpt

Nectins are immunoglobulin-like cell adhesion molecules mainly localized in adherens junctions. The transcription factor p63 is a master regulator of gene expression in stratified epithelia and controls several molecular processes. As mutations in the Pvrl1 and Pvrl4 genes encoding for nectins cause genetic disorders with phenotypes similar to p63-related syndromes, we investigated whether these proteins might be...

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Identifiers

PMID: 25387952
DOI: 10.1111/exd.12593
PMCID: PMC4329386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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