Molecular cloning of a monkeypox virus clade IIb genome and construction of an attenuated mutant for basic and translational research.

doi:10.1080/22221751.2026.2717859

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Molecular cloning of a monkeypox virus clade IIb genome and construction of an attenuated mutant for basic and translational research.

Emerging microbes & infections - 1 Dec 2026

Klatt Vincent, Meyer Zu Natrup Christian, Staliunaite Laura, Clever Sabrina, Knickmann Jan, Ohrnberger Sonja, Seib Jan, Ostermann Eleonore, Weichel Hanna-Marie, Addo Marylyn M, Volz Asisa, Brune Wolfram

Abstract excerpt

Monkeypox virus (MPXV) is a rodent-borne orthopoxvirus causing mpox disease upon zoonotic transmission to humans. Recent global outbreaks have raised awareness and highlighted the need for basic and translational research. However, research is hampered by the classification of MPXV as a Risk Group 3 pathogen. In an effort to overcome this limitation, we generated a complete full-length MPXV clade IIb bacterial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Artificial, Bacterial
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CAST gene

Share to Genome, Viral

Share to Mice

Share to Mutation

Share to Thymidine Kinase

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 42647848
DOI: 10.1080/22221751.2026.2717859
PMCID: PMC13520863

Genes

CAST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.