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Reduced production of OprM may promote oprD mutations and lead to imipenem resistance in Pseudomonas aeruginosa carrying an oprD-group 1A allele.

Microbial drug resistance (Larchmont, N.Y.) - 1 Apr 2015

Shu Jwu-Ching, Su Lin-Hui, Chiu Cheng-Hsun, Kuo An-Jing, Liu Tsui-Ping, Lee Ming-Hsun, Su I-Ning, Wu Tsu-Lan

Abstract excerpt

Resistance mechanisms in a group of carbapenemase-negative Pseudomonas aeruginosa that were susceptible to all antibiotics except carbapenems (carbapenem resistance-only P. aeruginosa [CROPA]) were studied. Ten genetically nonrelated CROPA isolates and their carbapenem-susceptible counterparts were further investigated. OprD production was demonstrated by protein electrophoresis in only 1 of the 10...

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PMID: 25386722
DOI: 10.1089/mdr.2014.0116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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