Article
Mutational analysis of angiogenin gene in Parkinson's disease.
PloS one - 1 Jan 2014
Chen Meng-Ling, Wu Ruey-Meei, Tai Chun-Hwei, Lin Chin-Hsien
Abstract excerpt
Mutations in the angiogenic factor, angiogenin (ANG), have been identified in patients with both familial and sporadic amyotrophic lateral sclerosis (ALS) and are thought to have a neuroprotective function. Parkinsonism has been noted in kindreds with ANG mutations and variants in the ANG gene have been found to associate with PD in two Caucasian populations. We therefore hypothesized that mutations in ANG may...
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