Article
Identification of a novel missense mutation in angiogenin in a Chinese amyotrophic lateral sclerosis cohort.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases - 1 May 2012
Zou Zhang-Yu, Wang Xin-Ning, Liu Ming-Sheng, Sun Qin, Li Xiao-Guang, Cui Li-Ying, Kong Jiming
Abstract excerpt
Abstract Angiogenin (ANG) gene mutations have been identified in both familial and sporadic amyotrophic lateral sclerosis (ALS) patients from multiple European and North American populations. However, no ANG mutation has yet been reported in Asian ALS populations. Here, we screened for ANG mutations in a Chinese ALS cohort. The entire coding region of the ANG gene was sequenced in 10 familial ALS pedigrees, 202...
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