Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of novel Angiogenin (ANG) gene missense variants in German patients with amyotrophic lateral sclerosis.

Journal of neurology - 1 Aug 2009

Fernández-Santiago Rubén, Hoenig Sabine, Lichtner Peter, Sperfeld Anne-Dorte, Sharma Manu, Berg Daniela, Weichenrieder Oliver, Illig Thomas, Eger Katharina, Meyer Thomas, Anneser Johanna, Münch Christoph, Zierz Stephan, Gasser Thomas, Ludolph Albert

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disease characterized by the selective death of motor neurons in the motor cortex, brain stem and spinal cord. Recently, missense variants in the angiogenin gene (ANG), an angiogenic factor expressed in ventral horn motor neurons that is up-regulated by hypoxia, have been found in ALS patients of Irish/Scottish, North American, Italian,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to Central Nervous System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germany

Share to Hypoxia

Share to Mutation, Missense

Share to Oxidative Stress

Share to Ribonuclease, Pancreatic

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 19363631
DOI: 10.1007/s00415-009-5124-4
PMCID: PMC2921066

Genes

ANG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of novel Angiogenin (ANG) gene missense variants in German patients with amyotrophic lateral sclerosis.PMID 19363631Read ↗

Identification of new ANG gene mutations in a large cohort of Italian patients with amyotrophic lateral sclerosis.Semantic proximity Read ↗

Identification of a novel missense mutation in angiogenin in a Chinese amyotrophic lateral sclerosis cohort.Semantic proximity Read ↗

A novel Angiogenin gene mutation in a sporadic patient with amyotrophic lateral sclerosis from southern Italy.Semantic proximity Read ↗

Mutations of the ANG gene in French patients with sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

[The association between angiogenin gene variations and familial amyotrophic lateral sclerosis in Chinese Han patients].Semantic proximity Read ↗

Effects of Pathogenic Mutants of the Neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS).Semantic proximity Read ↗

Screening of hypoxia-inducible genes in sporadic ALS.Semantic proximity Read ↗

Angiogenin levels and ANG genotypes: dysregulation in amyotrophic lateral sclerosis.Semantic proximity Read ↗

Angiogenin loss-of-function mutations in amyotrophic lateral sclerosis.Semantic proximity Read ↗

Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis.Semantic proximity Read ↗

Lack of association between the Angiogenin (ANG) rs11701 polymorphism and amyotrophic lateral sclerosis risk: a meta-analysis.Semantic proximity Read ↗

Association between the Angiogenin (ANG) K17I variant and amyotrophic lateral sclerosis risk in Caucasian: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.