Article
Regulatory B Cells and Its Role in Central Nervous System Inflammatory Demyelinating Diseases.
Frontiers in immunology - 1 Jan 2020
Ran Zhou, Yue-Bei Luo, Qiu-Ming Zeng, Huan Yang
Abstract excerpt
Regulatory B (Breg) cells represent a population of suppressor B cells that participate in immunomodulatory processes and inhibition of excessive inflammation. The regulatory function of Breg cells have been demonstrated in mice and human with inflammatory diseases, cancer, after transplantation, and particularly in autoinflammatory disorders. In order to suppress inflammation, Breg cells produce...
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