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Article

Genetic diversity of CYP3A4 and CYP3A5 polymorphisms in North African populations from Morocco and Tunisia.

The International journal of biological markers - 24 Feb 2015

Novillo Apolonia, Romero-Lorca Alicia, Gaibar María, Bahri Raoudha, Harich Nourdin, Sánchez-Cuenca David, Esteban Esther, Fernández-Santander Ana

Abstract excerpt

The genes CYP3A4 and CYP3A5 form part of a cluster of cytochrome P450 genes involved in drug metabolism reactions. The allelic variants of these genes CYP3A4*1B, CYP3A4*3, CYP3A4*17 and CYP3A5*3 have been linked both to the reduced catalytic activity of cytochromes and to prostate cancer risk in whites, though scarce data exist for North African populations. The main objective of this study was to describe...

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PMID: 25385241
DOI: 10.5301/jbm.5000118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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