Article
Polymorphisms in CYP17 and CYP3A4 and prostate cancer in men of African descent.
The Prostate - 1 May 2013
Taioli Emanuela, Sears Vestra, Watson Alexis, Flores-Obando Rafael E, Jackson Maria D, Ukoli Flora A, de Syllos Cólus Ilce M, Fernandez Pedro, McFarlane-Anderson Norma, Ostrander Elaine A, Rodrigues Iara S, Stanford Janet L, Taylor Jack A, Tulloch-Reid Marshall, Ragin Camille C R
Abstract excerpt
BACKGROUND: A meta and pooled analysis of published and unpublished case-control studies was performed to evaluate the association of CYP17 (rs743572) and CYP3A4 (rs2740574) polymorphisms and prostate cancer (PCa) in men from the USA, Caribbean, and Africa. METHODS: Eight publications (seven studies) and two unpublished studies for CYP17 included 1,580 subjects (559 cases and 1,021 controls) and eleven...
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