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Article

p53 suppresses 14-3-3γ by stimulating proteasome-mediated 14-3-3γ protein degradation.

International journal of oncology - 1 Feb 2015

Chen De-Yu, Dai Dong-Fang, Hua Ye, Qi Wen-Qing

Abstract excerpt

14-3-3 proteins are a family of highly conserved polypeptides that interact with a large number of proteins and play a role in a wide variety of cellular processes. 14-3-3 proteins have been demonstrated overexpressed in several cancers and serving as potential oncogenes. In a previous study we showed one isoform of the 14-3-3 family, 14-3-3γ was negatively regulated by p53 through binding to its promoter and...

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Identifiers

PMID: 25384678
DOI: 10.3892/ijo.2014.2740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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