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Article

14-3-3sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma.

Molecular cancer therapeutics - 1 Feb 2006

Yang Huiling, Zhao Ruiying, Lee Mong-Hong

Abstract excerpt

The 14-3-3sigma gene product, up-regulated by p53 in response to DNA damage, is involved in cell-cycle checkpoint control and is a human cancer epithelial marker down-regulated in various tumors. However, its role and function have not been established in nasopharyngeal carcinoma (NPC), a tumor of epithelial origin. Recently, we found that 14-3-3sigma interacts with p53 in response to DNA damage and stabilizes...

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Identifiers

PMID: 16505098
DOI: 10.1158/1535-7163.MCT-05-0395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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14-3-3sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma.PMID 16505098Read ↗

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