Article
P53 suppresses expression of the 14-3-3 gamma oncogene.
BMC cancer - 25 Aug 2011
Radhakrishnan Vijayababu M, Putnam Charles W, Qi Wenqing, Martinez Jesse D
Abstract excerpt
BACKGROUND: 14-3-3 proteins are a family of highly conserved proteins that are involved in a wide range of cellular processes. Recent evidence indicates that some of these proteins have oncogenic activity and that they may promote tumorigenesis. We previously showed that one of the 14-3-3 family members, 14-3-3 gamma, is over expressed in human lung cancers and that it can induce transformation of rodent cells in...
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