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Article

Enabling the 'host jump': structural determinants of receptor-binding specificity in influenza A viruses.

Nature reviews. Microbiology - 1 Dec 2014

Shi Yi, Wu Ying, Zhang Wei, Qi Jianxun, Gao George F

Abstract excerpt

The recent emergence of the H7N9 avian influenza A virus and its ability to infect humans emphasize the epidemic and pandemic potential of these viruses. Interspecies transmission is the result of many factors, which ultimately lead to a change in the host tropism of the virus. One of the key factors involved is a shift in the receptor-binding specificity of the virus, which is mostly determined by mutations in...

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Source

Identifiers

PMID: 25383601
DOI: 10.1038/nrmicro3362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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