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Article

Structural basis for receptor specificity of influenza B virus hemagglutinin

17 Oct 2007

Abstract excerpt

Receptor-binding specificity of HA, the major surface glycoprotein of influenza virus, primarily determines the host ranges that the virus can infect. Influenza type B virus almost exclusively infects humans and contributes to the annual "flu" sickness. Here we report the structures of influenza B virus HA in complex with human and avian receptor analogs, respectively. These structures provide a structural basis...

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PMID: 17942670
DOI: 10.1073/pnas.0708363104

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