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Article

Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors.

Nature - 16 Nov 2006

Yamada Shinya, Suzuki Yasuo, Suzuki Takashi, Le Mai Q, Nidom Chairul A, Sakai-Tagawa Yuko, Muramoto Yukiko, Ito Mutsumi, Kiso Maki, Horimoto Taisuke, Shinya Kyoko, Sawada Toshihiko, Kiso Makoto, Usui Taiichi, Murata Takeomi, Lin Yipu, Hay Alan, Haire Lesley F, Stevens David J, Russell Rupert J, Gamblin Steven J, Skehel John J, Kawaoka Yoshihiro

Abstract excerpt

H5N1 influenza A viruses have spread to numerous countries in Asia, Europe and Africa, infecting not only large numbers of poultry, but also an increasing number of humans, often with lethal effects. Human and avian influenza A viruses differ in their recognition of host cell receptors: the former preferentially recognize receptors with saccharides terminating in sialic acid-alpha2,6-galactose (SAalpha2,6Gal),...

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PMID: 17108965
DOI: 10.1038/nature05264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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