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Article

An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level.

Science (New York, N.Y.) - 21 Jun 2013

Zhang Wei, Shi Yi, Lu Xishan, Shu Yuelong, Qi Jianxun, Gao George F

Abstract excerpt

Recent studies have identified several mutations in the hemagglutinin (HA) protein that allow the highly pathogenic avian H5N1 influenza A virus to transmit between mammals by airborne route. Here, we determined the complex structures of wild-type and mutant HAs derived from an Indonesia H5N1 virus bound to either avian or human receptor sialic acid analogs. A cis/trans conformational change in the glycosidic...

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Source

Identifiers

PMID: 23641058
DOI: 10.1126/science.1236787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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