Article
Common variants in the MKL1 gene confer risk of schizophrenia.
Schizophrenia bulletin - 1 May 2015
Luo Xiong-Jian, Huang Liang, Oord Edwin J van den, Aberg Karolina A, Gan Lin, Zhao Zhongming, Yao Yong-Gang
Abstract excerpt
Genome-wide association studies (GWAS) of schizophrenia have identified multiple risk variants with robust association signals for schizophrenia. However, these variants could explain only a small proportion of schizophrenia heritability. Furthermore, the effect size of these risk variants is relatively small (eg, most of them had an OR less than 1.2), suggesting that additional risk variants may be detected when...
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