Article
Genome-wide association study and polygenic risk score analysis for schizophrenia in a Korean population.
Asian journal of psychiatry - 1 Dec 2024
Lee Dongbin, Baek Ji Hyun, Kim Yujin, Lee Byung Dae, Cho Eun-Young, Joo Eun-Jeong, Ahn Yong Min, Kim Se Hyun, Chung Young-Chul, Rami Fatima Zahra, Kim Se Joo, Kim Sung-Wan, Myung Woojae, Ha Tae Hyon, Lee Heon-Jeong, Oh Hayoung, Lee Kyu Young, Kim Min Ji, Kang Chae Yeong, Jeon Sumoa, Jo Anna, Yu Hyeona, Jeong Seunghwa, Ha Kyooseob, Kim Beomsu, Shim Injeong, Cho Chamlee, Huang Hailiang, Won Hong-Hee, Hong Kyung Sue
Abstract excerpt
Although large-scale genome-wide association studies (GWASs) have revealed the genetic architecture of schizophrenia, these studies have mainly focused on populations of European ancestry. This study aimed to identify common genetic variants associated with schizophrenia in the Korean population and evaluate the performance of polygenic risk scores (PRSs) derived from large-scale GWASs across ancestries. In the...
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