Article
Fine mapping by genetic association implicates the chromosome 1q23.3 gene UHMK1, encoding a serine/threonine protein kinase, as a novel schizophrenia susceptibility gene.
Biological psychiatry - 1 Apr 2007
Puri Vinay, McQuillin Andrew, Choudhury Khalid, Datta Susmita, Pimm Jonathan, Thirumalai Srinivasa, Krasucki Robert, Lawrence Jacob, Quested Digby, Bass Nicholas, Moorey Helen, Morgan Jenny, Punukollu Bhaskar, Kandasami Gomathinayagam, Curtis David, Gurling Hugh
Abstract excerpt
BACKGROUND: Linkage studies by us and others have confirmed that chromosome 1q23.3 is a susceptibility locus for schizophrenia. Based on this information, several research groups have published evidence that markers within both the RGS4 and CAPON genes, which are 700 kb apart, independently showe...
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