Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants within obesity-related genes are associated with tumor recurrence in patients with stages II/III colon cancer.

Pharmacogenetics and genomics - 1 Jan 2015

Sebio Ana, Gerger Armin, Matsusaka Satoshi, Yang Dongyun, Zhang Wu, Stremitzer Stefan, Stintzing Sebastian, Sunakawa Yu, Yamauchi Shinichi, Ning Yan, Fujimoto Yoshiya, Ueno Masashi, Lenz Heinz-Josef

Abstract excerpt

OBJECTIVE: Obesity is an established risk factor for colorectal cancer (CRC) incidence and it is also linked to CRC recurrence and survival. Polymorphisms located in obesity-related genes are associated with an increased risk of developing several cancer types including CRC. We evaluated whether single-nucleotide polymorphisms in obesity-related genes may predict tumor recurrence in colon cancer patients....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Colonic Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Muscle Proteins

Share to Neoplasm Recurrence, Local

Share to Neoplasm Staging

Share to Obesity

Share to PPAR alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 25379721
DOI: 10.1097/FPC.0000000000000101
PMCID: PMC4260998

Genes

DRG1
LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants within obesity-related genes are associated with tumor recurrence in patients with stages II/III colon cancer.PMID 25379721Read ↗

Plastin polymorphisms predict gender- and stage-specific colon cancer recurrence after adjuvant chemotherapy.Semantic proximity Read ↗

Association of miRNA targetome variants in LAMC1 and GNB3 genes with colorectal cancer and obesity.Semantic proximity Read ↗

PTGS2 polymorphism rs689466 favors breast cancer recurrence in obese patients.Semantic proximity Read ↗

Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer.Semantic proximity Read ↗

PTEN-induced kinase 1 gene single-nucleotide variants as biomarkers in adjuvant chemotherapy for colorectal cancerSemantic proximity Read ↗

Association of lncRNA MEG3 rs941576 polymorphism, expression profile, and its related targets with the risk of obesity-related colorectal cancer: potential clinical insights.Semantic proximity Read ↗

Association of C-reactive protein gene polymorphisms and colorectal cancer.Semantic proximity Read ↗

Association between polymorphism near the MC4R gene and cancer risk: A meta-analysis.Semantic proximity Read ↗

Gly972Arg variant of insulin receptor substrate 1 gene and colorectal cancer risk in overweight/obese subjects.Semantic proximity Read ↗

Association between adiponectin polymorphisms and the risk of colorectal cancer.Semantic proximity Read ↗

Resistin -420C>G promoter variant and colorectal cancer risk.Semantic proximity Read ↗

GWAS-identified colorectal cancer susceptibility loci associated with clinical outcomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.