Article
Resistin -420C>G promoter variant and colorectal cancer risk.
The International journal of biological markers - 30 Sept 2014
Mahmoudi Touraj, Karimi Khatoon, Arkani Maral, Farahani Hamid, Vahedi Mohsen, Dabiri Reza, Nobakht Hossein, Asadi Asadollah, Mirakhorli Mojgan, Arshi Benafsheh, Derakhshan Arash, Zali Mohammad Reza
Abstract excerpt
PURPOSES: Obesity is associated with an increased risk of colorectal cancer (CRC), and ghrelin (GHRL) and resistin (RETN) are thought to be related to obesity. Our aim was to investigate whether GHRL and RETN gene variants are associated with CRC risk. MATERIALS AND METHODS: All 414 subjects, including 197 cases with CRC and 217 controls, were genotyped for the GHRL (rs26802) and RETN (rs1862513) or -420 C>G gene...
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