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Article

Brain atrophy rates in first degree relatives at risk for Alzheimer's.

NeuroImage. Clinical - 1 Jan 2014

Lampert Erika J, Roy Choudhury Kingshuk, Hostage Christopher A, Rathakrishnan Bharath, Weiner Michael, Petrella Jeffrey R, Doraiswamy P Murali

Abstract excerpt

A positive family history (FH) raises the risk for late-onset Alzheimer's disease though, other than the known risk conferred by apolipoprotein ε4 (ApoE4), much of the genetic variance remains unexplained. We examined the effect of family history on longitudinal regional brain atrophy rates in 184 subjects (42% FH+, mean age 79.9) with mild cognitive impairment (MCI) enrolled in a national biomarker study. An...

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Identifiers

PMID: 25379448
DOI: 10.1016/j.nicl.2014.08.024
PMCID: PMC4215425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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