Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia.

Neurobiology of aging - 1 Jul 2020

Dounavi Maria-Eleni, Mak Elijah, Wells Katie, Ritchie Karen, Ritchie Craig W, Su Li, O' Brien John T

Abstract excerpt

The hippocampus is one of the first regions to demonstrate atrophy during the prodromal stage of Alzheimer's disease. Volumetric analysis of its individual subfields could provide biomarkers with higher sensitivity than whole hippocampal volume during an earlier disease stage. We quantified the hippocampal subfields volume in a large cohort comprising healthy participants (aged 40-59) with dementia family history...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Atrophy
Share to Dementia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diffusion Magnetic Resonance Imaging

Share to Educational Status

Share to Hippocampus

Share to Organ Size

Source

Identifiers

PMID: 32311609
DOI: 10.1016/j.neurobiolaging.2020.03.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia.PMID 32311609Read ↗

Associations between Alzheimer’s disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participantsSemantic proximity Read ↗

Associations between Alzheimer’s disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participantsSemantic proximity Read ↗

Differences in hippocampal subfield volume are seen in phenotypic variants of early onset Alzheimer's diseaseSemantic proximity Read ↗

Hippocampal volumes in UK Biobank are associated with APOE only in older adultsSemantic proximity Read ↗

The human hippocampus and its subfield volume across age, sex and APOE e4 statusSemantic proximity Read ↗

Family history of Alzheimer's disease and hippocampal structure in healthy people.Semantic proximity Read ↗

Hippocampal volumes in UK Biobank are associated with APOE only in older adultsSemantic proximity Read ↗

Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease.Semantic proximity Read ↗

The effect of age and smoking on the hippocampus and memory in late middle age.Semantic proximity Read ↗

The selective vulnerability of the left fimbria in cognitively normal APOE ε4 carriers: a localized structural correlate of high genetic risk for Alzheimer's disease.Semantic proximity Read ↗

Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumesSemantic proximity Read ↗

Hippocampal Subregions are Differentially Affected in the Progression to Alzheimer's DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.