Article
Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release.
Bioscience reports - 12 Dec 2014
Guilfoyle Amy P, Deshpande Chandrika N, Schenk Gerhard, Maher Megan J, Jormakka Mika
Abstract excerpt
GDP release from GTPases is usually extremely slow and is in general assisted by external factors, such as association with guanine exchange factors or membrane-embedded GPCRs (G protein-coupled receptors), which accelerate the release of GDP by several orders of magnitude. Intrinsic factors can...
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