Article
The initiation of GTP hydrolysis by the G-domain of FeoB: insights from a transition-state complex structure.
PloS one - 1 Jan 2011
Ash Miriam-Rose, Maher Megan J, Guss J Mitchell, Jormakka Mika
Abstract excerpt
The polytopic membrane protein FeoB is a ferrous iron transporter in prokaryotes. The protein contains a potassium-activated GTPase domain that is essential in regulating the import of iron and conferring virulence to many disease-causing bacteria. However, the mechanism by which the G-domain of...
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