Article
Occupation of nucleotide in the binding pocket is critical to the stability of Rab11A.
Protein expression and purification - 1 Apr 2016
Shin Young-Cheul, Kim Chang Min, Choi Jae Young, Jeon Ju-Hong, Park Hyun Ho
Abstract excerpt
The Ras superfamily of small G proteins is a family of guanosine triphosphatases (GTPases) and each GTPase has conserved amino acid sequences in the enzymatic active site that are responsible for specific interactions with GDP and GTP molecules. Rab GTPases, which belong to the Ras superfamily, are key regulators of intracellular vesicle trafficking via the recruitment of effector molecules. Here, we purified...
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