Article
A suite of Switch I and Switch II mutant structures from the G-protein domain of FeoB.
Acta crystallographica. Section D, Biological crystallography - 1 Nov 2011
Ash Miriam Rose, Maher Megan J, Guss J Mitchell, Jormakka Mika
Abstract excerpt
The acquisition of ferrous iron in prokaryotes is achieved by the G-protein-coupled membrane protein FeoB. This protein possesses a large C-terminal membrane-spanning domain preceded by two soluble cytoplasmic domains that are together termed 'NFeoB'. The first of these soluble domains is a GTPase domain (G-domain), which is then followed by an entirely α-helical domain. GTP hydrolysis by the G-domain is...
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