Article
The structure of an N11A mutant of the G-protein domain of FeoB.
Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Dec 2011
Ash Miriam Rose, Maher Megan J, Guss J Mitchell, Jormakka Mika
Abstract excerpt
The uptake of ferrous iron in prokaryotes is mediated by the G-protein-coupled membrane protein FeoB. The protein contains two N-terminal soluble domains that are together called `NFeoB'. One of these is a G-protein domain, and GTP hydrolysis by this domain is essential for iron transport. The GTPase activity of NFeoB is accelerated in the presence of potassium ions, which bind at a site adjacent to the...
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