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Article

Development of a genetic marker set to diagnose aspirin-exacerbated respiratory disease in a genome-wide association study.

The pharmacogenomics journal - 1 Aug 2015

Chang H S, Shin S W, Lee T H, Bae D J, Park J S, Kim Y H, Uh S T, Choi B W, Kim M K, Choi I S, Park B L, Shin H D, Park C S

Abstract excerpt

We developed a genetic marker set of single nucleotide polymorphisms (SNPs) by summing risk scores of 14 SNPs showing a significant association with aspirin-exacerbated respiratory disease (AERD) from our previous 660 W genome-wide association data. The summed scores were higher in the AERD than in the aspirin-tolerant asthma (ATA) group (P=8.58 × 10(-37)), and were correlated with the percent decrease in forced...

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Identifiers

PMID: 25707394
DOI: 10.1038/tpj.2014.78

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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