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Article

Dipeptidyl-peptidase 10 as a genetic biomarker for the aspirin-exacerbated respiratory disease phenotype.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Mar 2015

Kim Seung-Hyun, Choi Hyunna, Yoon Moon-Gyung, Ye Young-Min, Park Hae-Sim

Abstract excerpt

BACKGROUND: Aspirin-exacerbated respiratory disease (AERD) is an endotype of severe and eosinophilic adult asthma characterized by chronic rhinosinusitis with nasal polyps and hypersensitivity to aspirin and/or nonsteroidal anti-inflammatory drugs. A genetic contribution of dipeptidyl-peptidase 10 (DPP10) to asthma susceptibility and lung function decline has been reported. However, little is known about the role...

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Identifiers

PMID: 25592153
DOI: 10.1016/j.anai.2014.12.003

Genes

DPP10

Provenance

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