Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A modified recombineering protocol for the genetic manipulation of gene clusters in Aspergillus fumigatus.

PloS one - 1 Jan 2014

Alcazar-Fuoli Laura, Cairns Timothy, Lopez Jordi F, Zonja Bozo, Pérez Sandra, Barceló Damià, Igarashi Yasuhiro, Bowyer Paul, Bignell Elaine

Abstract excerpt

Genomic analyses of fungal genome structure have revealed the presence of physically-linked groups of genes, termed gene clusters, where collective functionality of encoded gene products serves a common biosynthetic purpose. In multiple fungal pathogens of humans and plants gene clusters have been shown to encode pathways for biosynthesis of secondary metabolites including metabolites required for pathogenicity....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspergillus fumigatus
Share to Chromosomes, Artificial, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Order

Share to Genes, Fungal

Share to Genetic Engineering

Share to Host-Pathogen Interactions

Share to Macrophages

Share to Multigene Family

Source

Open in PubMed Open full text

Identifiers

PMID: 25372385
DOI: 10.1371/journal.pone.0111875
PMCID: PMC4221250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A modified recombineering protocol for the genetic manipulation of gene clusters in Aspergillus fumigatus.PMID 25372385Read ↗

Drivers of genetic diversity in secondary metabolic gene clusters within a fungal speciesSemantic proximity Read ↗

A PCR-based strategy to generate integrative targeting alleles with large regions of homology.Semantic proximity Read ↗

A novel method used to delete a new Aspergillus fumigatus ABC transporter-encoding gene.Semantic proximity Read ↗

Co-transformation of Aspergillus fumigatus: a simple and efficient strategy for gene editing without linking selectable markersSemantic proximity Read ↗

Co-transformation of Aspergillus fumigatus: a simple and efficient strategy for gene editing without linking selectable markersSemantic proximity Read ↗

Drivers of genetic diversity in secondary metabolic gene clusters within a fungal species.Semantic proximity Read ↗

A high-throughput gene disruption methodology for the entomopathogenic fungus Metarhizium robertsii.Semantic proximity Read ↗

Functional Reconstitution of a Fungal Natural Product Gene Cluster by Advanced Genome EditingSemantic proximity Read ↗

Trackable multiplex recombineering for gene-trait mapping in E. coli.Semantic proximity Read ↗

Deletion of Aspergillus nidulans aroC using a novel blaster module that combines ET cloning and marker rescue.Semantic proximity Read ↗

Aspergillus flavus Secondary Metabolites: More than Just AflatoxinsSemantic proximity Read ↗

Deletion analysis of the avermectin biosynthetic genes of Streptomyces avermitilis by gene cluster displacement.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.