Article

Drivers of genetic diversity in secondary metabolic gene clusters within a fungal species

2017-06-13

Abstract excerpt

<h4>Summary</h4> Filamentous fungi produce a diverse array of secondary metabolites (SMs) critical for defense, virulence, and communication. The metabolic pathways that produce SMs are found in contiguous gene clusters in fungal genomes, an atypical arrangement for metabolic pathways in other eukaryotes. Comparative studies of filamentous fungal species have shown that SM gene clusters are often either highly di...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: abf1f411-6748-5f87-a500-4854bcd31645
DOI: 10.1101/149856

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Drivers of genetic diversity in secondary metabolic gene clusters within a fungal speciesDOI 10.1101/149856Read

Drivers of genetic diversity in secondary metabolic gene clusters within a fungal species.Semantic proximity Read

Biosynthetic gene clusters, secondary metabolite profiles, and cards of virulence in the closest nonpathogenic relatives of <i>Aspergillus fumigatus</i>Semantic proximity Read

Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence Across Aspergillus Species.Semantic proximity Read

Fungal Gene Cluster Diversity and Evolution.Semantic proximity Read

Genetic Diversity of Human Fungal PathogensSemantic proximity Read

Microevolution in the pansecondary metabolome of Aspergillus flavus and its potential macroevolutionary implications for filamentous fungiSemantic proximity Read

Giant transposons promote strain heterogeneity in a major fungal pathogenSemantic proximity Read

Complex Evolutionary Origins of Specialized Metabolite Gene Cluster Diversity among the Plant Pathogenic Fungi of the Fusarium graminearum Species ComplexSemantic proximity Read

Complex evolutionary origins of specialized metabolite gene cluster diversity among the plant pathogenic fungi of the <i>Fusarium graminearum</i> species complexSemantic proximity Read

Giant transposons promote strain heterogeneity in a major fungal pathogen.Semantic proximity Read

Population genetics and microevolution of clinical Candida glabrata reveals recombinant sequence types and hyper-variation within mitochondrial genomes, virulence genes, and drug targetsSemantic proximity Read

Genomic and phenotypic trait variation of the opportunistic human pathogen <i>Aspergillus flavus</i> and its non-pathogenic close relativesSemantic proximity Read