Article
Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities.
Circulation. Cardiovascular genetics - 1 Dec 2014
Chan Kei Hang K, Huang Yen-Tsung, Meng Qingying, Wu Chunyuan, Reiner Alexander, Sobel Eric M, Tinker Lesley, Lusis Aldons J, Yang Xia, Liu Simin
Abstract excerpt
BACKGROUND: Although cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D) share many common risk factors, potential molecular mechanisms that may also be shared for these 2 disorders remain unknown. METHODS AND RESULTS: Using an integrative pathway and network analysis, we performed genome-wide association studies in 8155 blacks, 3494 Hispanic American, and 3697 Caucasian American women who...
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