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Article

Role of IGF1-(CA)19 promoter microsatellite in the clinical presentation of acromegaly.

European journal of clinical investigation - 1 Dec 2014

Sala Elisa, Filopanti Marcello, Ferrante Emanuele, Barbieri Anna Maria, Malchiodi Elena, Verrua Elisa, Giavoli Claudia, Lania Andrea G, Arosio Maura, Beck-Peccoz Paolo, Spada Anna, Mantovani Giovanna

Abstract excerpt

BACKGROUND: A highly polymorphic Cytosine-Adenosine (CA) repeat sequence microsatellite has been identified in the promoter region of IGF1 gene. Several studies investigated the relationship between IGF1-(CA)n polymorphism and IGF1 levels, with conflicting results. Aim of this study was to investigate the influence of this polymorphism on clinical and biochemical characteristics of acromegalic patients. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25370837
DOI: 10.1111/eci.12366

Genes

IGF1
SDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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